Molecular and Cellular Mechanisms of Photocarcinogenesis
نویسندگان
چکیده
منابع مشابه
Molecular mechanisms of photocarcinogenesis.
Photocarcinogenesis represents the accumulation of genetic changes as well as immune system modulation, which ultimately lead to the development of skin cancers. The recent advances in molecular and cellular biology have clarified the mechanisms of photocarcinogenesis, including the formation of DNA photoproducts, DNA repair, mutation of proto-oncogenes and tumor suppressor genes, and UV-induce...
متن کاملPhotocarcinogenesis--molecular mechanisms.
The carcinogenicity (photocarcinogenicity) of sunlight to human skin has been recognized more than a century ago. Last decades numerous experimental studies show that UV rays damage DNA, cause gene mutations leading to the development of malignant tumors such basal cell carcinomas, squamous cell carcinomas and melanomas. The tumors occur most frequently in fair skinned people, and the mutations...
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Introduction: Spinal cord injury (SCI) following traumatic events is associated with the limited therapeutic options and sever complications, which can be partly due to inflammatory response. Therefore, this study aims to explore the role of inflammation in spinal cord injury. The findings showed that the pathological conditions of nervous system lead to activation of microglia, astrocyte, neut...
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ژورنال
عنوان ژورنال: Photochemistry and Photobiology
سال: 2007
ISSN: 0031-8655,1751-1097
DOI: 10.1111/j.1751-1097.2007.00231.x